Registration Open for GBCC2025:
Joint Galaxy/Bioconductor Conference!
Abstract Submission for Posters closes May 1!

TCGAbiolinks

This is the released version of TCGAbiolinks; for the devel version, see TCGAbiolinks.

TCGAbiolinks: An R/Bioconductor package for integrative analysis with GDC data


Bioconductor version: Release (3.21)

The aim of TCGAbiolinks is : i) facilitate the GDC open-access data retrieval, ii) prepare the data using the appropriate pre-processing strategies, iii) provide the means to carry out different standard analyses and iv) to easily reproduce earlier research results. In more detail, the package provides multiple methods for analysis (e.g., differential expression analysis, identifying differentially methylated regions) and methods for visualization (e.g., survival plots, volcano plots, starburst plots) in order to easily develop complete analysis pipelines.

Author: Antonio Colaprico, Tiago Chedraoui Silva, Catharina Olsen, Luciano Garofano, Davide Garolini, Claudia Cava, Thais Sabedot, Tathiane Malta, Stefano M. Pagnotta, Isabella Castiglioni, Michele Ceccarelli, Gianluca Bontempi, Houtan Noushmehr

Maintainer: Tiago Chedraoui Silva <tiagochst at gmail.com>, Antonio Colaprico <axc1833 at med.miami.edu>

Citation (from within R, enter citation("TCGAbiolinks")):

Installation

To install this package, start R (version "4.5") and enter:

 if (!require("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("TCGAbiolinks") 

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("TCGAbiolinks")
1. IntroductionHTMLR Script
10. ClassifiersHTMLR Script
10. TCGAbiolinks_ExtensionHTMLR Script
11. Stemness scoreHTMLR Script
2. Searching GDC databaseHTMLR Script
3. Downloading and preparing files for analysisHTMLR Script
4. Clinical dataHTMLR Script
5. Mutation dataHTMLR Script
6. Compilation of TCGA molecular subtypesHTMLR Script
7. Analyzing and visualizing TCGA dataHTMLR Script
8. Case StudiesHTMLR Script
Reference ManualPDF
NEWSText

Details

biocViewsDNAMethylation, DifferentialExpression, DifferentialMethylation, GeneExpression, GeneRegulation, MethylationArray, Network, Pathways, Sequencing, Software, Survival
Version2.36.0
In Bioconductor sinceBioC 3.2 (R-3.2) (9.5 years)
LicenseGPL (>= 3)
DependsR (>= 4.1.0)
Importsdownloader (>= 0.4), grDevices, biomaRt, dplyr, graphics, tibble, GenomicRanges, XML (>= 3.98.0), data.table, jsonlite (>= 1.0.0), plyr, knitr, methods, ggplot2, stringr (>= 1.0.0), IRanges, rvest (>= 0.3.0), stats, utils, S4Vectors, R.utils, SummarizedExperiment(>= 1.4.0), TCGAbiolinksGUI.data(>= 1.15.1), readr, tools, tidyr, purrr, xml2, httr (>= 1.2.1)
System Requirements
URLhttps://github.com/BioinformaticsFMRP/TCGAbiolinks
Bug Reportshttps://github.com/BioinformaticsFMRP/TCGAbiolinks/issues
See More
Suggestsjpeg, png, BiocStyle, rmarkdown, devtools, maftools, parmigene, c3net, minet, Biobase, affy, testthat, sesame, AnnotationHub, ExperimentHub, pathview, clusterProfiler, Seurat, ComplexHeatmap, circlize, ConsensusClusterPlus, igraph, supraHex, limma, edgeR, sva, EDASeq, survminer, genefilter, gridExtra, survival, doParallel, parallel, ggrepel (>= 0.6.3), scales, grid, DT
Linking To
Enhances
Depends On Me
Imports MeELMER, MoonlightR, SurfR, TENET, SingscoreAMLMutations, CureAuxSP, oncoPredict
Suggests MeGeoTcgaData, iNETgrate, musicatk
Links To Me
Build ReportBuild Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source PackageTCGAbiolinks_2.36.0.tar.gz
Windows Binary (x86_64) TCGAbiolinks_2.36.0.zip
macOS Binary (x86_64)TCGAbiolinks_2.36.0.tgz
macOS Binary (arm64)
Source Repositorygit clone https://git.bioconductor.org/packages/TCGAbiolinks
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/TCGAbiolinks
Bioc Package Browserhttps://code.bioconductor.org/browse/TCGAbiolinks/
Package Short Urlhttps://bioconductor.org/packages/TCGAbiolinks/
Package Downloads ReportDownload Stats
Old Source Packages for BioC 3.21Source Archive
close