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IgGeneUsage

This is the released version of IgGeneUsage; for the devel version, see IgGeneUsage.

Differential gene usage in immune repertoires


Bioconductor version: Release (3.21)

Detection of biases in the usage of immunoglobulin (Ig) genes is an important task in immune repertoire profiling. IgGeneUsage detects aberrant Ig gene usage between biological conditions using a probabilistic model which is analyzed computationally by Bayes inference. With this IgGeneUsage also avoids some common problems related to the current practice of null-hypothesis significance testing.

Author: Simo Kitanovski [aut, cre]

Maintainer: Simo Kitanovski <simo.kitanovski at uni-due.de>

Citation (from within R, enter citation("IgGeneUsage")):

Installation

To install this package, start R (version "4.5") and enter:

 if (!require("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("IgGeneUsage") 

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("IgGeneUsage")
User Manual: IgGeneUsageHTMLR Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViewsBayesian, BiomedicalInformatics, DifferentialExpression, Genetics, ImmunoOncology, MathematicalBiology, Regression, Software
Version1.22.0
In Bioconductor sinceBioC 3.10 (R-3.6) (5.5 years)
LicenseMIT + file LICENSE
DependsR (>= 4.2.0)
Importsmethods, reshape2 (>= 1.4.3), Rcpp (>= 0.12.0), RcppParallel (>= 5.0.1), rstan (>= 2.18.1), rstantools (>= 2.2.0), SummarizedExperiment, tidyr
System RequirementsGNU make
URLhttps://github.com/snaketron/IgGeneUsage
Bug Reportshttps://github.com/snaketron/IgGeneUsage/issues
See More
SuggestsBiocStyle, knitr, rmarkdown, testthat (>= 2.1.0), ggplot2, ggforce, ggrepel, patchwork
Linking ToBH (>= 1.66.0), Rcpp (>= 0.12.0), RcppEigen (>= 0.3.3.3.0), RcppParallel (>= 5.0.1), rstan (>= 2.18.1), StanHeaders (>= 2.18.0)
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source PackageIgGeneUsage_1.22.0.tar.gz
Windows Binary (x86_64) IgGeneUsage_1.22.0.zip
macOS Binary (x86_64)IgGeneUsage_1.22.0.tgz
macOS Binary (arm64)IgGeneUsage_1.22.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/IgGeneUsage
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/IgGeneUsage
Bioc Package Browserhttps://code.bioconductor.org/browse/IgGeneUsage/
Package Short Urlhttps://bioconductor.org/packages/IgGeneUsage/
Package Downloads ReportDownload Stats
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