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HiLDA

This is the released version of HiLDA; for the devel version, see HiLDA.

Conducting statistical inference on comparing the mutational exposures of mutational signatures by using hierarchical latent Dirichlet allocation


Bioconductor version: Release (3.21)

A package built under the Bayesian framework of applying hierarchical latent Dirichlet allocation. It statistically tests whether the mutational exposures of mutational signatures (Shiraishi-model signatures) are different between two groups. The package also provides inference and visualization.

Author: Zhi Yang [aut, cre], Yuichi Shiraishi [ctb]

Maintainer: Zhi Yang <zyang895 at gmail.com>

Citation (from within R, enter citation("HiLDA")):

Installation

To install this package, start R (version "4.5") and enter:

 if (!require("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("HiLDA") 

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("HiLDA")
An introduction to HiLDAHTMLR Script
Reference ManualPDF
NEWSText
INSTALLText

Details

biocViewsBayesian, Sequencing, Software, SomaticMutation, StatisticalMethod
Version1.22.0
In Bioconductor sinceBioC 3.10 (R-3.6) (5.5 years)
LicenseGPL-3
DependsR (>= 4.1), ggplot2
ImportsR2jags, abind, cowplot, grid, forcats, stringr, GenomicRanges, S4Vectors, XVector, Biostrings, GenomicFeatures, BSgenome.Hsapiens.UCSC.hg19, BiocGenerics, tidyr, grDevices, stats, TxDb.Hsapiens.UCSC.hg19.knownGene, utils, methods, Rcpp
System RequirementsJAGS 4.0.0
URLhttps://github.com/USCbiostats/HiLDAhttps://doi.org/10.1101/577452
Bug Reportshttps://github.com/USCbiostats/HiLDA/issues
See More
Suggestsknitr, rmarkdown, testthat, BiocStyle
Linking ToRcpp
Enhances
Depends On Me
Imports MeselectKSigs
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source PackageHiLDA_1.22.0.tar.gz
Windows Binary (x86_64) HiLDA_1.22.0.zip
macOS Binary (x86_64)HiLDA_1.22.0.tgz
macOS Binary (arm64)HiLDA_1.22.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/HiLDA
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/HiLDA
Bioc Package Browserhttps://code.bioconductor.org/browse/HiLDA/
Package Short Urlhttps://bioconductor.org/packages/HiLDA/
Package Downloads ReportDownload Stats
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