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HiCDCPlus

This is the released version of HiCDCPlus; for the devel version, see HiCDCPlus.

Hi-C Direct Caller Plus


Bioconductor version: Release (3.21)

Systematic 3D interaction calls and differential analysis for Hi-C and HiChIP. The HiC-DC+ (Hi-C/HiChIP direct caller plus) package enables principled statistical analysis of Hi-C and HiChIP data sets – including calling significant interactions within a single experiment and performing differential analysis between conditions given replicate experiments – to facilitate global integrative studies. HiC-DC+ estimates significant interactions in a Hi-C or HiChIP experiment directly from the raw contact matrix for each chromosome up to a specified genomic distance, binned by uniform genomic intervals or restriction enzyme fragments, by training a background model to account for random polymer ligation and systematic sources of read count variation.

Author: Merve Sahin [cre, aut] ORCID iD ORCID: 0000-0003-3858-8332

Maintainer: Merve Sahin <merve.sahn at gmail.com>

Citation (from within R, enter citation("HiCDCPlus")):

Installation

To install this package, start R (version "4.5") and enter:

 if (!require("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("HiCDCPlus") 

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("HiCDCPlus")
Analyzing Hi-C and HiChIP data with HiCDCPlusHTMLR Script
Reference ManualPDF
NEWSText

Details

biocViewsDNA3DStructure, HiC, Normalization, Software
Version1.16.0
In Bioconductor sinceBioC 3.13 (R-4.1) (4 years)
LicenseGPL-3
Depends
ImportsRcpp, InteractionSet, GenomicInteractions, bbmle, pscl, BSgenome, data.table, dplyr, tidyr, GenomeInfoDb, rlang, splines, MASS, GenomicRanges, IRanges, tibble, R.utils, Biostrings, rtracklayer, methods, S4Vectors
System RequirementsJRE 8+
URL
See More
SuggestsBSgenome.Mmusculus.UCSC.mm9, BSgenome.Mmusculus.UCSC.mm10, BSgenome.Hsapiens.UCSC.hg19, BSgenome.Hsapiens.UCSC.hg38, RUnit, BiocGenerics, knitr, rmarkdown, HiTC, DESeq2, Matrix, BiocFileCache, rappdirs
Linking ToRcpp
Enhancesparallel
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source PackageHiCDCPlus_1.16.0.tar.gz
Windows Binary (x86_64) HiCDCPlus_1.16.0.zip
macOS Binary (x86_64)HiCDCPlus_1.16.0.tgz
macOS Binary (arm64)HiCDCPlus_1.16.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/HiCDCPlus
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/HiCDCPlus
Bioc Package Browserhttps://code.bioconductor.org/browse/HiCDCPlus/
Package Short Urlhttps://bioconductor.org/packages/HiCDCPlus/
Package Downloads ReportDownload Stats
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