MLML2R: Maximum Likelihood Estimation of DNA Methylation and Hydroxymethylation Proportions

Maximum likelihood estimates (MLE) of the proportions of 5-mC and 5-hmC in the DNA using information from BS-conversion, TAB-conversion, and oxBS-conversion methods. One can use information from all three methods or any combination of two of them. Estimates are based on Binomial model by Qu et al. (2013) <doi:10.1093/bioinformatics/btt459> and Kiihl et al. (2019) <doi:10.1515/sagmb-2018-0031>.

Version:0.3.3
Suggests:minfi, microbenchmark, GEOquery, knitr, rmarkdown, IlluminaHumanMethylation450kmanifest
Published:2019-10-17
DOI:10.32614/CRAN.package.MLML2R
Author:Samara Kiihl [aut, cre], Maria Jose Martinez-Garrido [aut], Arce Domingo-Relloso [aut], Jose Bermudez [aut], Maria Tellez-Plaza [aut]
Maintainer:Samara Kiihl <samara at ime.unicamp.br>
BugReports:https://github.com/samarafk/MLML2R/issues
License:MIT + file LICENSE
URL:https://github.com/samarafk/MLML2R
NeedsCompilation:no
Citation:MLML2R citation info
CRAN checks:MLML2R results

Documentation:

Reference manual: MLML2R.pdf
Vignettes:Using MLML2R (source, R code)

Downloads:

Package source: MLML2R_0.3.3.tar.gz
Windows binaries: r-devel: MLML2R_0.3.3.zip, r-release: MLML2R_0.3.3.zip, r-oldrel: MLML2R_0.3.3.zip
macOS binaries: r-release (arm64): MLML2R_0.3.3.tgz, r-oldrel (arm64): MLML2R_0.3.3.tgz, r-release (x86_64): MLML2R_0.3.3.tgz, r-oldrel (x86_64): MLML2R_0.3.3.tgz
Old sources: MLML2R archive

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